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Gonadotropin preparations are drugs that mimic the physiological effects of gonadotropins, used therapeutically mainly as fertility medication for ovarian hyperstimulation and ovulation induction. For example, the so-called menotropins consist of LH and FSH extracted from human urine from menopausal women. Merck received approval on February 15, 2010, from the European Commission for ELONVA (corifollitropin alfa) a long-lasting single injection fusion protein lacking LH activity.

Elonva can produce side effects such as nausea, pelvic discomfort and pain, breast tenderness, and OHSS syndrome, according to a report published at drugs.com

"The most common side effects with Elonva are headache, nausea (feeling sick), tiredness, pelvic pain and discomfort, breast tenderness, and ovarian hyperstimulation syndrome (OHSS). OHSS occurs when the ovaries over-respond to treatment, causing abdominal swelling and pain, nausea, and diarrhea."

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