From Everything.Sucks

Senna glycoside, also known as sennoside or senna, is a medication used to treat constipation and empty the large intestine before surgery. The medication is taken by mouth or via the rectum. It typically begins working in minutes when given by rectum and within twelve hours when given by mouth. It is a weaker laxative than bisacodyl or castor oil.

A patient mentioned, "Senokot is an unpredictable laxative. I take pain pills for chronic pain. For years I took Magnesium Oxide which worked like a charm. However, I had to keep adjusting the dose & it finally stopped working altogether. After trying other laxatives unsuccessfully, I tried Senokot. Began with 2 pills: nothing. 3 pills: nothing. I finally took 4 pills & next day excruciating cramps & went 4 times. Stools were not soft &I had to strain despite taking stool softness (these have never worked alone but read that taken with Senokot helped). At my wits end because nothing aside from enemas work. I eat prunes, plenty of fruit, dried figs & tons of vegetables. I can't take the cramping side effect which I never had with Magnesium Oxide."

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