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From Everything.Sucks

A dermal adhesive (or skin glue) is a glue used to close wounds in the skin, as an alternative to sutures, staples or clips. Glued closure produces less scarring and is less prone to infection than sutured or stapled closure. There is also no residual closure to remove, so follow-up visits for removal are not required.

A case Reported by Arthur W. Perry about severe Allergic Reaction to Dermabond

Allergic reactions to 2-octyl cyanoacrylate rare in the medical literature; there is only one published report. However, scattered anecdotal reports of allergies to Dermabond on the Internet.

A healthy 36-year-old white woman with a deflated silicone gel–filled breast implant underwent uneventful removal of her implants, bilateral capsulotomies, replacement of her implants with 325-cc silicone gel–filled implants, and bilateral mastopexies. She received perioperative cefazolin, and the implants were bathed in bacitracin. Her wounds were closed with Vicryl sutures (Ethicon), deep dermal polydioxanone sutures (Ethicon), key sutures with Prolene (Ethicon), and Dermabond on the skin.

On a postoperative day one, she was seen routinely and was well. Three days postoperatively, she reported erythema around her incisions. Her husband, a physician, feared infection and prescribed 1 g of intramuscular ceftriaxone (Rocephin; Roche Laboratories, Nutley, NJ) and oral sulfamethoxazole/trimethoprim (Bactrim DS; Roche Laboratories). She was unable to see the surgeon on that day. The next morning, with worsening erythema and itching, she was seen in the emergency room by the surgeon. She was afebrile and looked well. All incisions were erythematous and pruritic, but not tender. Vesicles similar to those seen with poison ivy were visible throughout all incisions, extending only to the area where Dermabond was applied (Figure 1). An area where the Dermabond had dripped on the lateral side of her breast was also erythematous. An infectious disease specialist was consulted.

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