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From Everything.Sucks

Stiff-person syndrome (SPS), also known as stiff-man syndrome (SMS), is a rare neurologic disorder of unclear cause characterized by progressive rigidity and stiffness. Responsiveness to diazepam helps confirm that the patient is suffering from SPS, as this decreases stiffness and motor unit potential firing. Diazepam, first marketed as Valium, is a medicine of the benzodiazepine family that typically produces a calming effect.

Valium for SPS could cause many side effects such as blurred vision, pattern changes of speech, confusion, dark urine, difficulty to urinate and dizziness, according to a post published by

"Along with its needed effects, the active ingredient contained in Valium may cause some unwanted effects. If they do occur they may need medical attention. blurred vision, changes in patterns and rhythms of speech, chills, confusion, cough, dark urine, difficulty in passing urine, dizziness."

On the "National Center for Biotechnology Information, U.S. National Library of Medicine" website, "Alexander Muacevic" and "John R Adler" publish a journal titled "Recent Advances and Review on Treatment of Stiff Person Syndrome in Adults and Pediatric Patients" on Dec 22, 2015 in which analyze the use of Benzodiazepine (valium) as a treatment for the condition: "A divided dose of 5-100 mg of diazepam or clonazepam (divided dose 1-6 mg) are given by gradually increasing the dose over time. The administration of higher doses at the beginning of treatment may make patients susceptible to dangerous adverse effects, including respiratory depression along with drowsiness and dysarthria."


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